How Fasting Can Support Hormones, Muscle, And Heal The Body with Dr. Mindy Pelz | The Doctor's Farmacy with Mark Hyman, M.D. (2023)

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This episode is brought to you by Rupa Health, AG1, and Super Simple Grassfed Protein.It’s time to think about immunity in a new way. There’s been a lot of focus recently on “boosting” your immune system. However, boosting immunity merely exaggerates all the defects of an aging immune system, whereas rejuvenation reboots immunity from your cells up. Rejuvenation is way more foundational and longer lasting than a basic boost because it uses your built-in programming to rebalance and optimize that system’s function.In today’s episode of my series I’m calling Health Bites, I dive into immuno-rejuvenation—what it is, how it happens in the body, and my top strategies for switching it on.This episode is brought to you by Rupa Health and Super Simple Grassfed Protein.Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today.Head to drinkAG1.com/HYMAN to receive 10 FREE travel packs of AG1 with your first purchase.Right now, you can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and using code protein10.Here are more details from our interview (audio version / Apple Subscriber version):Why rejuvenation is better than the conventional approach to immune health (5:37 / 3:55)How rejuvenation happens in the body (7:06 / 4:22)Activating our body’s own immuno-rejuvenation (11:05 / 8:25)How positive stress is rejuvenating (13:38 / 11:22)Examples of positive stressors (16:52 / 14:37)Mentioned in this episodeBig Bold Health

01:12:45

This episode is brought to you by Rupa Health, BiOptimizers, LMNT, and Cozy Earth.Heart disease is still the number one killer in the world, yet most people don’t actually understand what markers put them most at risk.The general consensus is there are two types of cholesterol—the good and the bad—the good is thought to be high-density lipoproteins or HDL, and the bad is low-density lipoproteins or LDL. But we now know from research that it's much more complicated than that—there are actually various sizes and densities of these lipoproteins.Today on The Doctor’s Farmacy, I’m excited to talk to one of the leading lipidologists, Dr. Ronald Krauss, all about lipoproteins, what they do in the body, what they mean for heart disease risk, and why a typical lipid panel alone is insufficient.Dr. Krauss is a Senior Scientist at Children’s Hospital Oakland Research Institute, a Professor of Medicine at UCSF, and an Adjunct Professor of Nutritional Sciences at UC Berkeley. Dr. Krauss’s research aims to understand how to best prevent cardiovascular disease through early detection and management of its major risk factors: most notably, elevated levels of blood cholesterol and lipoproteins. He has published over 450 research articles and reviews on metabolic, genetic, dietary, and drug effects on plasma lipoproteins and the risk of coronary artery disease, with over 100,000 citations of this work.This episode is brought to you by Rupa Health, BiOptimizers, LMNT, and Cozy Earth.Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today.This month only you can get a FREE bottle of BiOptimizers Magnesium Breakthrough. Just go to magbreakthrough.com/hymanfree and enter coupon code hyman10.Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/hyman today.Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code DRHYMAN.Here are more details from our interview (audio version / Apple Subscriber version):How Dr. Krauss came to understand how cholesterol actually impacts the risk of heart disease (5:00 / 2:44)What is cholesterol? (9:00 / 6:37)Statins as heart disease treatment (13:36 / 11:29)Combatting myths around saturated fat (14:42 / 12:37)The assay Dr. Krauss developed to differentiate between the different sizes of lipoproteins and what they mean for heart disease risk (29:58 / 25:40)Testing beyond the standard lipid panel (39:51 / 35:31)Insulin resistance, prediabetes, and heart disease (46:35 / 41:50)Personal variation in heart disease risk (52:52 / 48:34)Dietary approaches to preventing heart disease (1:01:07 / 56:56)Research mentioned in this episode

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This episode is brought to you by Rupa University, Mitopure, Levels, and Super Simple Protein.Fatty liver is a dangerous yet misunderstood disease that is growing more and more common, and its effects are numerous. Fatty liver happens when fat replaces your liver cells and thereby compromises its important functions, thus increasing inflammation in the body. Surprisingly, it is not fat that causes a fatty liver, but sugar and starch.In today’s episode, I talk with Dr. Elizabeth Boham, Dr. Robert Lustig, and Shawn Stevenson about the importance of our liver and how to support it.Dr. Elizabeth Boham is a physician and nutritionist who practices Functional Medicine at The UltraWellness Center in Lenox, MA. Through her practice and lecturing she has helped thousands of people achieve their goals of optimum health and wellness. She witnesses the power of nutrition every day in her practice and is committed to training other physicians to utilize nutrition in healing.Dr. Robert Lustig is a neuroendocrinologist with expertise in metabolism, obesity, and nutrition. He’s the Emeritus Professor of Pediatrics in the Division of Endocrinology and a member of the Institute for Health Policy Studies at UCSF. He is also one of the leaders of the current “anti-sugar” movement that is changing the food industry, in part through his game-changing books.Shawn Stevenson is the author of the international bestselling book Sleep Smarter and creator of The Model Health Show, featured as the number one health podcast in the US, with millions of listener downloads each year. A graduate of the University of Missouri–St. Louis, Shawn studied business, biology, and nutritional science and went on to found Advanced Integrative Health Alliance, a company that provides wellness services for individuals and organizations worldwide.This episode is brought to you by Rupa University, Mitopure, Levels, and Super Simple Protein.If you’re a healthcare provider who wants to learn more about Functional Medicine testing, go to rupauniversity.com to sign up for a free live class or a boot camp!Support the growth of new, healthy mitochondria and get 10% off of Mitopure. Head to timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout.Right now, Levels is offering an additional two free months of their annual membership. Head over to levels.link/HYMAN to learn more.You can get 10% off Super Simple Grassfed Protein with the code protein10 at drhyman.com/protein.Full-length episodes (and corresponding links) of these interviews can be found here:Dr. Elizabeth BohamDr. Mark HymanDr. Robert LustigShawn Stevenson

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This episode is brought to you by Rupa University, Pique, and Super Simple Grassfed Protein.Our gut bacteria regulate many of our bodily functions, from creating vitamins to regulating our immune system, our brain function, and of course, our metabolism and weight. They are critical to our long-term health. One such bacteria is Akkermansia muciniphila, which accounts for 1%–5% of our gut microbiome—or at least it’s supposed to!In today’s episode of my series I’m calling Health Bites, I dive into Akkermansia—what it is, what role it plays in chronic disease prevention, and what you can do to increase it.This episode is brought to you by Rupa University, Pique, and Super Simple Grassfed Protein.If you’re a healthcare provider who wants to learn more about Functional Medicine testing, go to rupauniversity.com to sign up for a free live class or a boot camp!For a limited time, get up to 12% off plus an exclusive gift on Pique’s Fasting Tea bundle. Just go to Piquelife.com/farmacyfasting today.Right now, you can get 10% off Super Simple Grassfed Protein by heading to drhyman.com/protein and using code protein10.Here are more details from our interview (audio version / Apple Subscriber version):Healing my own gut and recovering my health (4:12 / 2:46)What is Akkermansia, and how does it work? (7:54 / 5:12)Akkermansia and chronic disease prevention (13:48 / 11:46)Foods that increase Akkermansia (24:26 / 22:20)Mentioned in this episodePendulum Akkermansia

01:09:24

This episode is brought to you by Rupa Health, ButcherBox, ARMRA Colostrum, and Apollo.So many of us struggle with relationships. In fact, our relationships determine the quality of our life more than anything else. Unfortunately, the relationships many of us grew up around–and might consider “normal”--are, in fact, dysfunctional, creating a negative cycle we often don’t even realize we’re in.Today on The Doctor’s Farmacy, I’m excited to talk to Nedra Tawwab about how to identify dysfunctional patterns in our relationships and what we can do to break the cycle and move forward.Nedra Glover Tawwab is the author of the New York Times bestsellers Drama Free and Set Boundaries, Find Peace. A licensed therapist and sought-after relationship expert, she has practiced relationship therapy for more than fifteen years. Nedra has appeared as an expert on Red Table Talk, The Breakfast Club, Good Morning America, and CBS Morning Show to name a few. Her work has been highlighted in The New York Times, The Guardian, and Vice, and has appeared on numerous podcasts, including The School of Greatness, We Can Do Hard Things, and Ten Percent Happier. Nedra runs a popular Instagram account where she shares practices, tools, and reflections for mental health and relationships.This episode is brought to you by Rupa Health, ButcherBox, ARMRA Colostrum, and Apollo.​​Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today.For new members of ButcherBox, you can receive New York Strip Steaks for a year PLUS $20 off your first order. Go to Butcherbox.com/farmacy and use code FARMACY.Receive 15% off your first order of ARMRA Colostrum. Go to tryarmra.com/MARK or enter MARK to get 15% off your first order.Visit apolloneuro.com/drhyman to save $40 on Apollo's wearable device.Here are more details from our interview (audio version / Apple Subscriber version):Setting boundaries as a people-pleaser (5:35 / 2:45)How to recognize and unlearn family dysfunction (8:13 / 6:17)How childhood trauma impacts adult relationships (15:27 / 13:12)Changing relationships by setting boundaries (18:54 / 16:30)The connection between sleep issues and relationship issues (26:26 / 22:40)Tools for shifting our relationships and patterns (28:38 / 24:41)Toxic forgiveness (36:17 / 32:20)Impacting change in others (58:45 / 52:08)Breaking family patterns in parenting (1:00:48 / 57:23)Learn more at nedratawwab.com and @nedratawwab. Get a copy of Drama Free: A Guide to Managing Unhealthy Family Relationships.

01:03:34

This episode is brought to you by Rupa Health, AG1, HigherDOSE, and Super Simple Grassfed Protein.We all know that life gets busy, but to stay healthy, you have to have a set of nonnegotiables that you make time for daily. Prioritizing food as medicine, establishing a consistent sleep routine, and cultivating community can all offer immense benefits, not only for your quality of life but your overall health and well-being too.In today’s episode, I talk with Dhru Purohit and Radha Agrawal about these three things that you can choose to focus on to level up your health.Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset.Radha Agrawal is the cofounder, CEO, and Chief Community Architect of Daybreaker, the early-morning dance and wellness movement. Daybreaker currently holds events in 25 cities and more than a dozen college campuses around the world and has a community of almost half a million people. She is also the author of a new book called Belong: Find Your People, Create Community, and Live a More Connected Life. In this episode, Radha makes a case for community.This episode is brought to you by Rupa Health, AG1, HigherDOSE, and Super Simple Grassfed Protein.Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.AG1 contains 75 high-quality vitamins, minerals, whole-food-sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN.Elevate your wellness game today by going to HigherDOSE.com. You can use promo code HYMAN at checkout to save 15% off site-wide or just go to HigherDOSE.com/hyman.Right now, you can get 10% off Super Simple Grassfed Protein with the code protein10 at drhyman.com/protein.Full-length episodes (and corresponding links) of these interviews can be found here:Dhru Purohit “How To Use Food As Medicine”Dhru Purohit “Why Sleep is More Important Than Diet”Radha Agrawal “The Most Important Medicine For Your Health and Longevity”

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This episode is brought to you by Rupa Health and AG1.One key area of focus on your health you may not have thought to pay attention to is the dangers of advanced glycation end products. In fact, you may not have even been aware of their existence at all. Advanced glycation end products (AGEs for short) are compounds that can form when you cook food at high temperatures. Depending on your diet and overall health, they can start to build up in your body, which can be a big problem since they've been linked to a range of health problems from diabetes to cardiovascular disease.In today’s episode of my series I’m calling Health Bites, I dive into the science behind AGEs and what you can do to protect yourself from their deleterious effects.This episode is brought to you by Rupa Health and AG1.Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.AG1 contains 75 high-quality vitamins, minerals, whole-food sourced superfoods, probiotics, and adaptogens to support your entire body. Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN.Here are more details from our interview (audio version / Apple Subscriber version):What are advanced glycation end products? (3:57 / 1:38)Where do AGEs come from? (5:59 / 2:56)Why AGEs are so bad (8:40 / 6:17)Reducing your AGE intake (9:19 / 6:56)Mentioned in this episodeThe 10-Day Detox

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This episode is brought to you by Rupa Health, BiOptimizers, Sensate, and Zero Acre.Hidden inflammation is at the root of all chronic illness—conditions like heart disease, obesity, diabetes, dementia, depression, and cancer. So if inflammation is at the root of most modern diseases, how do we find the causes and get the body back in balance?Today on The Doctor’s Farmacy, I’m excited to talk to Dr. Shilpa Ravella about what is driving our epidemic of inflammation and inflammaging, why it plagues so many people, and what we can do to combat it.Dr. Ravella is a gastroenterologist and Assistant Professor of Medicine at Columbia University Medical Center. She is the author of A Silent Fire: The Story of Inflammation, Diet & Disease, which investigates inflammation—the hidden force at the heart of modern disease. Her writing has appeared in The Atlantic, New York Magazine, The Wall Street Journal, TIME, Slate, Discover, and USA Today, among other publications.This episode is brought to you by Rupa Health, BiOptimizers, Sensate, and Zero Acre.Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.This month only you can get a FREE bottle of BiOptimizers’ full-spectrum magnesium supplement. To get your free bottle just go to magbreakthrough.com/hymanfree and enter coupon code hyman10. That’s it!I love my Sensate device. Whenever I use it, my mind calms down and I find myself getting more and better-quality sleep. Head on over to getsensate.com/Farmacy and use code FARMACY to get 10% off your Sensate device today.Zero Acre Oil is an all-purpose cooking oil with more healthy monounsaturated fat and significantly less inflammatory omega-6 fat than even avocado or olive oil. Go to zeroacre.com/MARK or use code MARK to redeem an exclusive offer.Here are more details from our interview (audio version / Apple Subscriber version):Helpful and harmful inflammation (5:18 / 2:46)How to know if you’re inflamed (7:37 / 4:46)Diagnostic testing to assess inflammation (10:11 / 9:00)What is driving our chronic inflammation? (14:59 / 12:42)The health of our gut microbiome and inflammation (20:17 / 17:47)Stress, loneliness, and inflammation (25:44 / 21:47)How environmental toxins drive inflammation (27:56 / 23:57)The rise in food allergies and sensitivities (30:30 / 26:59)Reducing inflammation in the body (38:06 / 33:34)Anti-inflammatory foods and supplements (49:52 / 45:30)Get a copy of A Silent Fire: The Story of Inflammation, Diet & Disease.

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This episode is brought to you by AG1, Pendulum, BiOptimizers, and Super Simple Grassfed Protein.If we were to identify one big lever to pull to improve global health, create economic abundance, restore environmental health, and reverse climate change, it would be transforming our entire food system. The policies and industry interests that drive our current system must change to fix our broken food system from field to fork and beyond.In today’s episode, I talk with Calley Means, Robby Sansom, Taylor Collins, and Dhru Purohit about industry funding that influences the results of food studies, marketing, and government policy.Calley Means is the cofounder of TrueMed, a company that enables Americans to buy exercise equipment and healthy food with FSA/HSA dollars. He is also the coauthor (with his sister, Dr. Casey Means) of an upcoming book on food as medicine. Earlier in his career, he was a consultant for food and pharma companies; he is now exposing the practices they use to weaponize our institutions of trust.Robby Sansom is cofounder and CEO at Force of Nature, a regeneratively sourced meat company based in Austin, TX. Force of Nature works in partnership with land stewards, ranchers, and farmers committed to creating a positive return on the planet. Robby is also a land steward at ROAM Ranch, where he owns regeneratively managed bison.Taylor Collins is the Chief Bison Wrangler and a cofounder at Force of Nature. In 2017, Taylor and his family purchased ROAM Ranch, a 900-acre multispecies regenerative ecosystem. Within five years of management, the ranch has seen dramatic improvements in soil carbon, water infiltration, plant diversity, and soil health.Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset.This episode is brought to you by AG1, Pendulum, BiOptimizers, and Super Simple Grassfed Protein.Right now, AG1 is offering 10 FREE travel packs with your first purchase by visiting drinkAG1.com/HYMAN.Pendulum is offering my listeners 20% off their first month of an Akkermansia subscription with code HYMAN at Pendulumlife.com.This month only you can get a FREE bottle of BiOptimizers’ full-spectrum magnesium supplement at magbreakthrough.com/hymanfree using coupon code hyman10.Get 10% off Super Simple Grassfed Protein with the code protein10 at drhyman.com/protein.Full-length episodes of these interviews can be found here:Calley MeansRobby Sansom and Taylor CollinsDhru Purohit